Granger因果关系（GC）检验是一种著名的统计假设检验，用于研究一个时期的过去是否影响了另一个时间的未来。它有助于回答一个问题序列是否有助于预测。 Granger因果关系检测的标准传统方法通常假设线性动力学，但是这种简化在许多现实世界应用中不存在，例如，神经科学或基因组学本质上是非线性的。在这种情况下，施加线性模型，例如向量自回旋（VAR）模型可能会导致对真正的Granger因果相互作用的不一致估计。机器学习（ML）可以学习数据集中的隐藏模式（DL）在学习复杂系统的非线性动力学方面表现出巨大的希望。 Tank等人的最新工作建议通过使用神经网络结合对可学习的权重的稀疏性惩罚来克服VAR模型中线性简化的问题。在这项工作中，我们基于Tank等人引入的想法。我们提出了几类新的模型，这些模型可以处理潜在的非线性。首先，我们介绍了学识渊博的内核var（lekvar）模型 - var模型的扩展，这些模型也学习了通过神经网络参数的内核。其次，我们表明可以通过脱钩的惩罚直接将滞后和单个时间序列的重要性分解。这种去耦提供了更好的缩放，并使我们可以将滞后选择嵌入RNN中。最后，我们提出了一种支持迷你批次的新培训算法，并且它与常用的自适应优化器（例如Adam）兼容。癫痫患者的电脑电图（EEG）数据研究了在19个EEG通道之前，期间和之后的GC演变。

Migraine is a high-prevalence and disabling neurological disorder. However, information migraine management in real-world settings could be limited to traditional health information sources. In this paper, we (i) verify that there is substantial migraine-related chatter available on social media (Twitter and Reddit), self-reported by migraine sufferers; (ii) develop a platform-independent text classification system for automatically detecting self-reported migraine-related posts, and (iii) conduct analyses of the self-reported posts to assess the utility of social media for studying this problem. We manually annotated 5750 Twitter posts and 302 Reddit posts. Our system achieved an F1 score of 0.90 on Twitter and 0.93 on Reddit. Analysis of information posted by our 'migraine cohort' revealed the presence of a plethora of relevant information about migraine therapies and patient sentiments associated with them. Our study forms the foundation for conducting an in-depth analysis of migraine-related information using social media data.

Key Point Analysis(KPA) is a relatively new task in NLP that combines summarization and classification by extracting argumentative key points (KPs) for a topic from a collection of texts and categorizing their closeness to the different arguments. In our work, we focus on the legal domain and develop methods that identify and extract KPs from premises derived from texts of judgments. The first method is an adaptation to an existing state-of-the-art method, and the two others are new methods that we developed from scratch. We present our methods and examples of their outputs, as well a comparison between them. The full evaluation of our results is done in the matching task -- match between the generated KPs to arguments (premises).

Are extralinguistic signals such as image pixels crucial for inducing constituency grammars? While past work has shown substantial gains from multimodal cues, we investigate whether such gains persist in the presence of rich information from large language models (LLMs). We find that our approach, LLM-based C-PCFG (LC-PCFG), outperforms previous multi-modal methods on the task of unsupervised constituency parsing, achieving state-of-the-art performance on a variety of datasets. Moreover, LC-PCFG results in an over 50% reduction in parameter count, and speedups in training time of 1.7x for image-aided models and more than 5x for video-aided models, respectively. These results challenge the notion that extralinguistic signals such as image pixels are needed for unsupervised grammar induction, and point to the need for better text-only baselines in evaluating the need of multi-modality for the task.

Dengue fever is a virulent disease spreading over 100 tropical and subtropical countries in Africa, the Americas, and Asia. This arboviral disease affects around 400 million people globally, severely distressing the healthcare systems. The unavailability of a specific drug and ready-to-use vaccine makes the situation worse. Hence, policymakers must rely on early warning systems to control intervention-related decisions. Forecasts routinely provide critical information for dangerous epidemic events. However, the available forecasting models (e.g., weather-driven mechanistic, statistical time series, and machine learning models) lack a clear understanding of different components to improve prediction accuracy and often provide unstable and unreliable forecasts. This study proposes an ensemble wavelet neural network with exogenous factor(s) (XEWNet) model that can produce reliable estimates for dengue outbreak prediction for three geographical regions, namely San Juan, Iquitos, and Ahmedabad. The proposed XEWNet model is flexible and can easily incorporate exogenous climate variable(s) confirmed by statistical causality tests in its scalable framework. The proposed model is an integrated approach that uses wavelet transformation into an ensemble neural network framework that helps in generating more reliable long-term forecasts. The proposed XEWNet allows complex non-linear relationships between the dengue incidence cases and rainfall; however, mathematically interpretable, fast in execution, and easily comprehensible. The proposal's competitiveness is measured using computational experiments based on various statistical metrics and several statistical comparison tests. In comparison with statistical, machine learning, and deep learning methods, our proposed XEWNet performs better in 75% of the cases for short-term and long-term forecasting of dengue incidence.

We present Masked Audio-Video Learners (MAViL) to train audio-visual representations. Our approach learns with three complementary forms of self-supervision: (1) reconstruction of masked audio and video input data, (2) intra- and inter-modal contrastive learning with masking, and (3) self-training by reconstructing joint audio-video contextualized features learned from the first two objectives. Pre-training with MAViL not only enables the model to perform well in audio-visual classification and retrieval tasks but also improves representations of each modality in isolation, without using information from the other modality for fine-tuning or inference. Empirically, MAViL sets a new state-of-the-art on AudioSet (53.1 mAP) and VGGSound (67.1% accuracy). For the first time, a self-supervised audio-visual model outperforms ones that use external supervision on these benchmarks. Code will be available soon.

Neural information retrieval (IR) systems have progressed rapidly in recent years, in large part due to the release of publicly available benchmarking tasks. Unfortunately, some dimensions of this progress are illusory: the majority of the popular IR benchmarks today focus exclusively on downstream task accuracy and thus conceal the costs incurred by systems that trade away efficiency for quality. Latency, hardware cost, and other efficiency considerations are paramount to the deployment of IR systems in user-facing settings. We propose that IR benchmarks structure their evaluation methodology to include not only metrics of accuracy, but also efficiency considerations such as a query latency and the corresponding cost budget for a reproducible hardware setting. For the popular IR benchmarks MS MARCO and XOR-TyDi, we show how the best choice of IR system varies according to how these efficiency considerations are chosen and weighed. We hope that future benchmarks will adopt these guidelines toward more holistic IR evaluation.

Semantic navigation is necessary to deploy mobile robots in uncontrolled environments like our homes, schools, and hospitals. Many learning-based approaches have been proposed in response to the lack of semantic understanding of the classical pipeline for spatial navigation, which builds a geometric map using depth sensors and plans to reach point goals. Broadly, end-to-end learning approaches reactively map sensor inputs to actions with deep neural networks, while modular learning approaches enrich the classical pipeline with learning-based semantic sensing and exploration. But learned visual navigation policies have predominantly been evaluated in simulation. How well do different classes of methods work on a robot? We present a large-scale empirical study of semantic visual navigation methods comparing representative methods from classical, modular, and end-to-end learning approaches across six homes with no prior experience, maps, or instrumentation. We find that modular learning works well in the real world, attaining a 90% success rate. In contrast, end-to-end learning does not, dropping from 77% simulation to 23% real-world success rate due to a large image domain gap between simulation and reality. For practitioners, we show that modular learning is a reliable approach to navigate to objects: modularity and abstraction in policy design enable Sim-to-Real transfer. For researchers, we identify two key issues that prevent today's simulators from being reliable evaluation benchmarks - (A) a large Sim-to-Real gap in images and (B) a disconnect between simulation and real-world error modes - and propose concrete steps forward.

DNA-Encoded Library (DEL) technology has enabled significant advances in hit identification by enabling efficient testing of combinatorially-generated molecular libraries. DEL screens measure protein binding affinity though sequencing reads of molecules tagged with unique DNA-barcodes that survive a series of selection experiments. Computational models have been deployed to learn the latent binding affinities that are correlated to the sequenced count data; however, this correlation is often obfuscated by various sources of noise introduced in its complicated data-generation process. In order to denoise DEL count data and screen for molecules with good binding affinity, computational models require the correct assumptions in their modeling structure to capture the correct signals underlying the data. Recent advances in DEL models have focused on probabilistic formulations of count data, but existing approaches have thus far been limited to only utilizing 2-D molecule-level representations. We introduce a new paradigm, DEL-Dock, that combines ligand-based descriptors with 3-D spatial information from docked protein-ligand complexes. 3-D spatial information allows our model to learn over the actual binding modality rather than using only structured-based information of the ligand. We show that our model is capable of effectively denoising DEL count data to predict molecule enrichment scores that are better correlated with experimental binding affinity measurements compared to prior works. Moreover, by learning over a collection of docked poses we demonstrate that our model, trained only on DEL data, implicitly learns to perform good docking pose selection without requiring external supervision from expensive-to-source protein crystal structures.

Fine-tuning pre-trained language models (PLMs) achieves impressive performance on a range of downstream tasks, and their sizes have consequently been getting bigger. Since a different copy of the model is required for each task, this paradigm is infeasible for storage-constrained edge devices like mobile phones. In this paper, we propose SPARTAN, a parameter efficient (PE) and computationally fast architecture for edge devices that adds hierarchically organized sparse memory after each Transformer layer. SPARTAN freezes the PLM parameters and fine-tunes only its memory, thus significantly reducing storage costs by re-using the PLM backbone for different tasks. SPARTAN contains two levels of memory, with only a sparse subset of parents being chosen in the first level for each input, and children cells corresponding to those parents being used to compute an output representation. This sparsity combined with other architecture optimizations improves SPARTAN's throughput by over 90% during inference on a Raspberry Pi 4 when compared to PE baselines (adapters) while also outperforming the latter by 0.1 points on the GLUE benchmark. Further, it can be trained 34% faster in a few-shot setting, while performing within 0.9 points of adapters. Qualitative analysis shows that different parent cells in SPARTAN specialize in different topics, thus dividing responsibility efficiently.